[{"data":1,"prerenderedAt":184},["ShallowReactive",2],{"notifications-general-en":3,"compound-CBD-en":4},"Due to summer holidays, the laboratory will operate on a revised schedule from July 22 to August 9, 2026. Analysis results may take 7 to 10 days from sample receipt. Thank you for your understanding.",{"name":5,"shortname":6,"synonyms":7,"cas":8,"molMass":9,"pubchemLink":10,"structure":11,"important":12,"synthetic":13,"compoundClass":14,"asociationImage":17,"summarySet":18,"compoundEffectSet":22},"Cannabidiol","CBD","cannabidiolum","13956-29-1",314.464,"https:\u002F\u002Fpubchem.ncbi.nlm.nih.gov\u002Fcompound\u002FCannabidiol","science\u002Fstructures\u002FCBD.png",true,false,{"id":15,"description":16},"2","Cannabinoids","",[19],{"summaryText":20,"language":21},"\u003Cp class=\"MsoNormal\" style=\"text-align:justify\">CBD, or cannabidiol, is a\r\nnon-intoxicating compound found in cannabis and hemp. CBD products are used to manage anxiety,\r\nstress, pain, and other symptoms. In the human body, CBD influences\r\ncannabinoid receptor activity and encourages production of the body’s natural\r\nendocannabinoids. Interestingly, CBD also affects activity beyond the\r\nendocannabinoid system and can also interact with  opioid, dopamine, and serotonin receptors.\r\nThe ability of CBD to interact with so many different systems throughout the\r\nbody suggests it has the potential to open new frontiers in psychiatry and medicine.\u003C\u002Fp>\u003Cp class=\"MsoNormal\" style=\"text-align:justify\">In 2018, CBD was FDA-approved\r\n(trade name Epidiolex) for the treatment of two forms of treatment-resistant\r\nepilepsy: Dravet syndrome and Lennox-Gastaut syndrome in children with\r\nrefractory epilepsy. While Epidiolex treatment is generally well tolerated, it\r\nis associated with minor adverse effects, such as gastrointestinal upset,\r\ndecreased appetite, sleepiness and lethargy, and poor sleep quality.\u003C\u002Fp>\u003Cp class=\"MsoNormal\" style=\"text-align:justify\">\u003Co:p>\u003C\u002Fo:p>\u003C\u002Fp>\u003Cp class=\"MsoNormal\" style=\"text-align:justify\">\u003Co:p>\u003C\u002Fo:p>\u003C\u002Fp>",null,[23,28,32,36,40,44,48,52,56,60,64,68,72,76,80,84,88,92,96,100,104,108,112,116,120,124,128,132,136,140,144,148,152,156,160,164,168,172,176,180],{"effectName":24,"LiteratureReferences":27},{"effectName":25,"effectType":26},"Anti inflamation - AD-related neuroinflammation","A_0","\u003Cp>\u003Ca href=\"http:\u002F\u002Fonlinelibrary.wiley.com\u002Fdoi\u002F10.1038\u002Fsj.bjp.0707337\u002Ffull\">Cannabidiol in vivo blunts β-amyloid induced neuroinflammation by suppressing IL-1β and iNOS expression\u003C\u002Fa>\u003Cbr>\u003C\u002Fp>",{"effectName":29,"LiteratureReferences":31},{"effectName":30,"effectType":26},"Anti Anxiety","\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.nature.com\u002Fnpp\u002Fjournal\u002Fv36\u002Fn6\u002Ffull\u002Fnpp20116a.html\">Cannabidiol Reduces the Anxiety Induced by Simulated Public Speaking in Treatment-Naïve Social Phobia Patients\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"http:\u002F\u002Fjournals.sagepub.com\u002Fdoi\u002Fabs\u002F10.1177\u002F0269881110379283\">Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report\u003C\u002Fa>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpmc\u002Farticles\u002FPMC5101100\u002F\">Effectiveness of Cannabidiol Oil for Pediatric Anxiety and Insomnia as Part of Posttraumatic Stress Disorder: A Case Report\u003C\u002Fa>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.nature.com\u002Fnpp\u002Fjournal\u002Fv36\u002Fn6\u002Ffull\u002Fnpp20116a.html\">Cannabidiol Reduces the Anxiety Induced by Simulated Public Speaking in Treatment-Naïve Social Phobia Patients\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs00213-008-1168-x\">Involvement of 5HT1A receptors in the anxiolytic-like effects of cannabidiol injected into the dorsolateral periaqueductal gray of rats\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs00213-012-2955-y\">Cannabidiol enhances consolidation of explicit fear extinction in humans\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F28553229\">Inverted U-Shaped Dose-Response Curve of the Anxiolytic Effect of Cannabidiol during Public Speaking in Real Life\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs00213-010-2036-z\">The anxiolytic-like effects of cannabidiol injected into the bed nucleus of the stria terminalis are mediated by 5-HT1A receptors\u003C\u002Fa>\u003Cbr>\u003Cbr>\u003Cbr>\u003Cbr>\u003Cbr>\u003C\u002Fp>",{"effectName":33,"LiteratureReferences":35},{"effectName":34,"effectType":26},"Anti diabetes and diabetic complications","\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F?term=27573936\">Efficacy and Safety of Cannabidiol and Tetrahydrocannabivarin on Glycemic and Lipid Parameters in Patients With Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Pilot Study\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"http:\u002F\u002Fajpheart.physiology.org\u002Fcontent\u002F293\u002F1\u002FH610.short\">Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption\u003C\u002Fa>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Ca href=\"http:\u002F\u002Fwww.onlinejacc.org\u002Fcontent\u002F56\u002F25\u002F2115\">Cannabidiol Attenuates Cardiac Dysfunction, Oxidative Stress, Fibrosis, and Inflammatory and Cell Death Signaling Pathways in Diabetic Cardiomyopathy\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"http:\u002F\u002Fajpheart.physiology.org\u002Fcontent\u002F293\u002F1\u002FH610.short\">Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003Cbr>\u003Cbr>\u003C\u002Fp>",{"effectName":37,"LiteratureReferences":39},{"effectName":38,"effectType":26},"Anti inflamation - Acute Pancreatitis","\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F22850623\">Anti-inflammatory role of cannabidiol and O-1602 in cerulein-induced acute pancreatitis in mice\u003C\u002Fa>\u003Cbr>\u003C\u002Fp>",{"effectName":41,"LiteratureReferences":43},{"effectName":42,"effectType":26},"Anti inflamation - acute respiratory sindrom (ARS)","\u003Cp>\u003Ca href=\"http:\u002F\u002Fwww.sciencedirect.com\u002Fscience\u002Farticle\u002Fpii\u002FS0014299912000052\">Cannabidiol, a non-psychotropic plant-derived cannabinoid, decreases inflammation in a murine model of acute lung injury: Role for the adenosine A2A receptor\u003C\u002Fa>\u003Cbr>\u003C\u002Fp>",{"effectName":45,"LiteratureReferences":47},{"effectName":46,"effectType":26},"Neuroprotectant - Alzheimer’s Disease","\u003Cp>\u003Ca href=\"https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs00109-005-0025-1\">The marijuana component cannabidiol inhibits β-amyloid-induced tau protein hyperphosphorylation through Wnt\u002Fβ-catenin pathway rescue in PC12 cells\u003C\u002Fa>\u003Cbr>\u003C\u002Fp>",{"effectName":49,"LiteratureReferences":51},{"effectName":50,"effectType":26},"Anorexia - Appetite Stimulant","\u003Cp>\u003Ca href=\"http:\u002F\u002Fcannabisplus.net\u002Fcannabis-research-pdf\u002FAlzheimers\u002FVolicer%20Effects%20of%20Dronabinol%20on%20Anorexia%20and%20Disturbed%20Behavior%20in%20Patients%20with%20Alzheimers%20Disease.pdf\">Effects of Dronabinol on Anorexia and disturbed behavior in patients with Alzheimer’s Disease\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"http:\u002F\u002Fwww.neurology.org\u002Fcontent\u002F84\u002F14_Supplement\u002FP6.039.short\">Cannabis Use in Epilepsy and Anorexia- Two “N-of-One” Trials (P6.039)\u003C\u002Fa>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Ca href=\"http:\u002F\u002Fcannabisplus.net\u002Fcannabis-research-pdf\u002FAlzheimers\u002FVolicer%20Effects%20of%20Dronabinol%20on%20Anorexia%20and%20Disturbed%20Behavior%20in%20Patients%20with%20Alzheimers%20Disease.pdf\">Effects of Dronabinol on Anorexia and disturbed behavior in patients with Alzheimer’s Disease\u003C\u002Fa>\u003Cbr>\u003C\u002Fp>",{"effectName":53,"LiteratureReferences":55},{"effectName":54,"effectType":26},"Appetite loss - Appetite Stimulant","\u003Cp>\u003Ca href=\"http:\u002F\u002Fwww.nature.com\u002Fnpp\u002Fjournal\u002Fv35\u002Fn9\u002Ffull\u002Fnpp201058a.html\">Cannabidiol attenuates the appetitive effects of Delta 9-tetrahydrocannabinol in humans smoking their chosen cannabis\u003C\u002Fa>\u003Cbr>\u003C\u002Fp>",{"effectName":57,"LiteratureReferences":59},{"effectName":58,"effectType":26},"Antiarthritic","\u003Cp>\u003Ca href=\"http:\u002F\u002Fwww.pnas.org\u002Fcontent\u002F97\u002F17\u002F9561.short\">The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis\u003C\u002Fa>\u003Cbr>\u003C\u002Fp>",{"effectName":61,"LiteratureReferences":63},{"effectName":62,"effectType":26},"Antibacterial","\u003Cp>\u003Ca href=\"https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007%2FBF00399444?LI=true\">Antibacterial activity of Δ9-tetrahydrocannabinol and cannabidiol\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007%2FBF00399444?LI=true\">Antibacterial activity of Δ9-tetrahydrocannabinol and cannabidiol\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"http:\u002F\u002Fpubs.acs.org\u002Fdoi\u002Fabs\u002F10.1021\u002Fnp8002673\">Antibacterial Cannabinoids from Cannabis sativa: A Structure−Activity Study\u003C\u002Fa>\u003Cbr>\u003Cbr>\u003Cbr>\u003C\u002Fp>",{"effectName":65,"LiteratureReferences":67},{"effectName":66,"effectType":26},"Neuroprotectant - Brain injury","\u003Cp>\u003Ca href=\"http:\u002F\u002Fpubs.acs.org\u002Fdoi\u002Fabs\u002F10.1021\u002Fnp8002673\">Antibacterial Cannabinoids from Cannabis sativa: A Structure−Activity Study\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"http:\u002F\u002Fjpet.aspetjournals.org\u002Fcontent\u002F314\u002F2\u002F780.short\">Comparison of Cannabidiol, Antioxidants, and Diuretics in Reversing Binge Ethanol-Induced Neurotoxicity\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.researchgate.net\u002Fprofile\u002FJose_Martinez-Orgado\u002Fpublication\u002F23148432_Neuroprotective_Effects_of_the_Nonpsychoactive_Cannabinoid_Cannabidiol_in_Hypoxic-Ischemic_Newborn_Piglets\u002Flinks\u002F00b7d538c6d0f32527000000.pdf\">Neuroprotective Effects of the Nonpsychoactive Cannabinoid Cannabidiol in Hypoxic-Ischemic Newborn Piglets\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"http:\u002F\u002Fwww.sciencedirect.com\u002Fscience\u002Farticle\u002Fpii\u002FS096999610900309X\">The neuroprotective effect of cannabidiol in an in vitro model of newborn hypoxic–ischemic brain damage in mice is mediated by CB2 and adenosine receptors\u003C\u002Fa>\u003Cbr>\u003Cbr>\u003Cbr>\u003Cbr>\u003C\u002Fp>",{"effectName":69,"LiteratureReferences":71},{"effectName":70,"effectType":26},"Antidyspnoea - Breathing difficulties","\u003Cp>\u003Ca href=\"http:\u002F\u002Fjournals.sagepub.com\u002Fdoi\u002Fabs\u002F10.1177\u002F1479972310391283\">Cannabinoid effects on ventilation and breathlessness: A pilot study of efficacy and safety\u003C\u002Fa>\u003Cbr>\u003C\u002Fp>",{"effectName":73,"LiteratureReferences":75},{"effectName":74,"effectType":26},"Anti Cancer","\u003Cp>\u003Ca href=\"http:\u002F\u002Fmct.aacrjournals.org\u002Fcontent\u002F13\u002F12\u002F2955.short\">The Combination of Cannabidiol and Δ9-Tetrahydrocannabinol Enhances the Anticancer Effects of Radiation in an Orthotopic Murine Glioma Model\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"https:\u002F\u002Facademic.oup.com\u002Fjnci\u002Farticle-abstract\u002F55\u002F3\u002F597\u002F912322\">In Vitro Anticancer Activity of Plant-Derived Cannabidiol on Prostate Cancer Cell Lines\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"http:\u002F\u002Fmct.aacrjournals.org\u002Fcontent\u002F13\u002F12\u002F2955.short\">The Combination of Cannabidiol and Δ9-Tetrahydrocannabinol Enhances the Anticancer Effects of Radiation in an Orthotopic Murine Glioma Model\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.researchgate.net\u002Fprofile\u002FManju_Sharma14\u002Fpublication\u002F276496424_In_Vitro_Anticancer_Activity_of_Plant-Derived_Cannabidiol_on_Prostate_Cancer_Cell_Line\u002Flinks\u002F586ec11608ae8fce491c8ed3\u002FIn-Vitro-Anticancer-Activity-of-Plant-Derived-Cannabidiol-on-Prostate-Cancer-Cell-Line.pdf\">Antineoplastic Activity of Cannabinoids\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs11626-013-9719-9\">Physiological intestinal oxygen modulates the Caco-2 cell model and increases sensitivity to the phytocannabinoid cannabidiol\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpmc\u002Farticles\u002FPMC3570006\u002F\">Non-THC cannabinoids inhibit prostate carcinoma growth in vitro and in vivo: pro-apoptotic effects and underlying mechanisms\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"http:\u002F\u002Fonlinelibrary.wiley.com\u002Fdoi\u002F10.1016\u002Fj.molonc.2014.12.010\u002Ffull\">Modulation of the tumor microenvironment and inhibition of EGF\u002FEGFR pathway: Novel anti-tumor mechanisms of Cannabidiol in breast cancer\u003C\u002Fa>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Ca href=\"http:\u002F\u002Fjpet.aspetjournals.org\u002Fcontent\u002F318\u002F3\u002F1375.short\">Antitumor Activity of Plant Cannabinoids with Emphasis on the Effect of Cannabidiol on Human Breast Carcinoma\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"http:\u002F\u002Fjpet.aspetjournals.org\u002Fcontent\u002F308\u002F3\u002F838.short\">Antitumor Effects of Cannabidiol, a Nonpsychoactive Cannabinoid, on Human Glioma Cell Lines\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"http:\u002F\u002Fonlinelibrary.wiley.com\u002Fdoi\u002F10.1038\u002Fsj.bjp.0706134\u002Ffull\">Cannabidiol inhibits human glioma cell migration through a cannabinoid receptor-independent mechanism\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"http:\u002F\u002Fjournals.plos.org\u002Fplosone\u002Farticle?id=10.1371\u002Fjournal.pone.0076918\">Cannabidiol, a Non-Psychoactive Cannabinoid Compound, Inhibits Proliferation and Invasion in U87-MG and T98G Glioma Cells through a Multitarget Effect\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs00109-011-0856-x\">Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer\u003C\u002Fa>\u003Cbr>\u003Cbr>\u003Ca href=\"http:\u002F\u002Fmct.aacrjournals.org\u002Fcontent\u002F10\u002F1\u002F90.short\">A Combined Preclinical Therapy of Cannabinoids and Temozolomide against Glioma\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fbooks\u002FNBK65755\u002F\" target=\"_blank\">Cannabis and Cannabinoids - PDQ Cancer Information Summaries\u003C\u002Fa>\u003Cbr>\u003Cbr>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003Cbr>\u003Cbr>\u003Cbr>\u003Cbr>\u003Cbr>\u003C\u002Fp>",{"effectName":77,"LiteratureReferences":79},{"effectName":78,"effectType":26},"Cardiac Proctection","\u003Cp>\u003Ca href=\"http:\u002F\u002Fwww.onlinejacc.org\u002Fcontent\u002F56\u002F25\u002F2115\">Cannabidiol Attenuates Cardiac Dysfunction, Oxidative Stress, Fibrosis, and Inflammatory and Cell Death Signaling Pathways in Diabetic Cardiomyopathy\u003C\u002Fa>\u003Cbr>\u003C\u002Fp>",{"effectName":81,"LiteratureReferences":83},{"effectName":82,"effectType":26},"Analgesic - Central Neuropathic Pain","\u003Cp>\u003Ca href=\"http:\u002F\u002Fwww.sciencedirect.com\u002Fscience\u002Farticle\u002Fpii\u002FS0149291807002949\">Oromucosal Δ9-tetrahydrocannabinol\u002Fcannabidiol for neuropathic pain associated with multiple sclerosis: An uncontrolled, open-label, 2-year extension trial\u003C\u002Fa>\u003Cbr>\u003C\u002Fp>",{"effectName":85,"LiteratureReferences":87},{"effectName":86,"effectType":26},"Antiinflammatory - Chronic pain","\u003Cp>\u003Ca href=\"http:\u002F\u002Fwww.sciencedirect.com\u002Fscience\u002Farticle\u002Fpii\u002FS001429990601257X\">The non-psychoactive cannabis constituent cannabidiol is an orally effective therapeutic agent in rat chronic inflammatory and neuropathic pain\u003C\u002Fa>\u003Cbr>\u003C\u002Fp>",{"effectName":89,"LiteratureReferences":91},{"effectName":90,"effectType":26},"Antidepresant","\u003Cp>\u003Ca href=\"http:\u002F\u002Fonlinelibrary.wiley.com\u002Fdoi\u002F10.1111\u002Fj.1476-5381.2009.00521.x\u002Ffull\">Antidepressant-like effects of cannabidiol in mice: possible involvement of 5-HT1A receptors\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F27010632\">Prohedonic Effect of Cannabidiol in a Rat Model of Depression\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F27010632\">Prohedonic Effect of Cannabidiol in a Rat Model of Depression\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"http:\u002F\u002Fwww.sciencedirect.com\u002Fscience\u002Farticle\u002Fpii\u002FS0166432816300298\">Antidepressant-like effect of cannabidiol injection into the ventral medial prefrontal cortex—Possible involvement of 5-HT1A and CB1 receptors\u003C\u002Fa>\u003Cbr>\u003Cbr>\u003Cbr>\u003Cbr>\u003C\u002Fp>",{"effectName":93,"LiteratureReferences":95},{"effectName":94,"effectType":26},"Antidystonic","\u003Cp>\u003Ca href=\"http:\u002F\u002Fwww.tandfonline.com\u002Fdoi\u002Fabs\u002F10.3109\u002F00207458608985678\">Open label evaluation of cannabidiol in dystonic movement disorders\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"http:\u002F\u002Fpsycnet.apa.org\u002Frecord\u002F1987-29054-001\">Cannabidiol in dystonic movement disorders\u003C\u002Fa>\u003Cbr>\u003Cbr>\u003C\u002Fp>",{"effectName":97,"LiteratureReferences":99},{"effectName":98,"effectType":26},"Antiepileptic","\u003Cp>\u003Ca href=\"http:\u002F\u002Fwww.sciencedirect.com\u002Fscience\u002Farticle\u002Fpii\u002FS105913111200057X\">Cannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F?term=26800377\">CBD-enriched medical cannabis for intractable pediatric epilepsy: The current Israeli experience\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F?term=26724101\">Cannabidiol in patients with treatment-resistant epilepsy: an open-label interventional trial\u003C\u002Fa>ž\u003C\u002Fp>\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.karger.com\u002FArticle\u002FAbstract\u002F137430\">Chronic administration of cannabidiol to healthy volunteers and epileptic patients\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"http:\u002F\u002Fonlinelibrary.wiley.com\u002Fdoi\u002F10.1111\u002Fepi.13499\u002Ffull\">Cannabidiol as a new treatment for drug-resistant epilepsy in tuberous sclerosis complex\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F27655472\">Cannabidiol as a Potential Treatment for Febrile Infection-Related Epilepsy Syndrome (FIRES) in the Acute and Chronic Phases\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"http:\u002F\u002Fwww.sciencedirect.com\u002Fscience\u002Farticle\u002Fpii\u002FS105913111200057X\">Cannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F25282526\">Cannabis, cannabidiol, and epilepsy–from receptors to clinical response\u003C\u002Fa>\u003Cbr>\u003Cbr>\u003Cbr>\u003Cbr>\u003Cbr>\u003Cbr>\u003Cbr>\u003C\u002Fp>",{"effectName":101,"LiteratureReferences":103},{"effectName":102,"effectType":26},"Improvement of recognition of emotional facial","\u003Cp>\u003Ca href=\"http:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F?term=Acute+effects+of+delta-9-tetrahydrocannabinol%2C+cannabidiol+and+their+combination+on+facial+emotion+recognition%3A+a+randomised%2C+double-blind%2C+placebo-controlled+study+in+cannabis+users\">Acute effects of delta-9-tetrahydrocannabinol, cannabidiol and their combination on facial emotion recognition: a randomised, double-blind, placebo-controlled study in cannabis users\u003C\u002Fa>\u003Cbr>\u003C\u002Fp>",{"effectName":105,"LiteratureReferences":107},{"effectName":106,"effectType":26},"Antiglaucoma","\u003Cp>\u003Ca href=\"http:\u002F\u002Fjournals.lww.com\u002Fglaucomajournal\u002FAbstract\u002F2006\u002F10000\u002FEffect_of_Sublingual_Application_of_Cannabinoids.1.aspx\">Effect of Sublingual Application of Cannabinoids on Intraocular Pressure: A Pilot Study\u003C\u002Fa>\u003Cbr>\u003C\u002Fp>",{"effectName":109,"LiteratureReferences":111},{"effectName":110,"effectType":26},"Neuroprotectant - Huntington’s Disease","\u003Cp>\u003Ca href=\"http:\u002F\u002Fwww.sciencedirect.com\u002Fscience\u002Farticle\u002Fpii\u002F009130579190386G\">Controlled clincal trial of cannabidiol in Huntington’s disease\u003C\u002Fa>\u003Cbr>\u003C\u002Fp>",{"effectName":113,"LiteratureReferences":115},{"effectName":114,"effectType":26},"Antipsychotic  - Hyperlocomotion","\u003Cp>\u003Ca href=\"http:\u002F\u002Fwww.sciencedirect.com\u002Fscience\u002Farticle\u002Fpii\u002FS0014299905002359\">Cannabidiol inhibits the hyperlocomotion induced by psychotomimetic drugs in mice\u003C\u002Fa>\u003Cbr>\u003C\u002Fp>",{"effectName":117,"LiteratureReferences":119},{"effectName":118,"effectType":26},"Auto-immunity - Immune System related diseases","\u003Cp>\u003Ca href=\"http:\u002F\u002Fwww.jpp.krakow.pl\u002Fjournal\u002Farchive\u002F10_09_s3\u002Fpdf\u002F99_10_09_s3_article.pdf\">Cannabidiol-induced Lymphopenia does not involve NKT and NK Cells\u003C\u002Fa>\u003Cbr>\u003C\u002Fp>",{"effectName":121,"LiteratureReferences":123},{"effectName":122,"effectType":26},"Anti-inflamation","\u003Cp>\u003Ca href=\"https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs00210-004-0871-3\">Oral anti-inflammatory activity of cannabidiol, a non-psychoactive constituent of cannabis, in acute carrageenan-induced inflammation in the rat paw\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"http:\u002F\u002Fiovs.arvojournals.org\u002Farticle.aspx?articleid=2164704\">Mediation of Cannabidiol Anti-inflammation in the Retina by Equilibrative Nucleoside Transporter and A2A Adenosine Receptor\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"http:\u002F\u002Fwww.sciencedirect.com\u002Fscience\u002Farticle\u002Fpii\u002FS0168365903004152\">Cannabidiol—transdermal delivery and anti-inflammatory effect in a murine model\u003C\u002Fa>\u003Cbr>\u003Cbr>\u003Cbr>\u003C\u002Fp>",{"effectName":125,"LiteratureReferences":127},{"effectName":126,"effectType":26},"Insomnia","\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpmc\u002Farticles\u002FPMC5101100\u002F\">Effectiveness of Cannabidiol Oil for Pediatric Anxiety and Insomnia as Part of Posttraumatic Stress Disorder: A Case Report\u003C\u002Fa>\u003Cbr>\u003C\u002Fp>",{"effectName":129,"LiteratureReferences":131},{"effectName":130,"effectType":26},"Multiple sclerosis","\u003Cp>\u003Ca href=\"http:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F23180178\">A double-blind, randomized, placebo-controlled, parallel-group study of THC\u002FCBD oromucosal spray in combination with the existing treatment regimen, in the relief of central neuropathic pain in patients with multiple sclerosis\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"http:\u002F\u002Fn.neurology.org\u002Fcontent\u002F65\u002F6\u002F812.short\">Randomized, controlled trial of cannabis-based medicine in central pain in multiple sclerosis\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"http:\u002F\u002Fonlinelibrary.wiley.com\u002Fdoi\u002F10.1016\u002Fj.ejpain.2008.05.014\u002Ffull\">Cannabinoid-induced effects on the nociceptive system: a neurophysiological study in patients with secondary progressive multiple sclerosis\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F?term=27003093\">The effect of cannabinoids on the stretch reflex in multiple sclerosis spasticity\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F24392812\">Clinical experience with THC:CBD oromucosal spray in patients with multiple sclerosis-related spasticity\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F24035293\">Clinical experiences with cannabinoids in spasticity management in multiple sclerosis\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"http:\u002F\u002Fjournals.sagepub.com\u002Fdoi\u002Fabs\u002F10.1191\u002F0269215503cr581oa\">A preliminary controlled study to determine whether whole-plant cannabis extracts can improve intractable neurogenic symptoms\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"http:\u002F\u002Fjournals.sagepub.com\u002Fdoi\u002Fabs\u002F10.1191\u002F1352458504ms1063oa\">An open-label pilot study of cannabis-based extracts for bladder dysfunction in advanced multiple sclerosis\u003C\u002Fa>\u003Cbr>\u003Cbr>\u003Cbr>\u003Cbr>\u003Cbr>\u003Cbr>\u003Cbr>\u003Cbr>\u003C\u002Fp>",{"effectName":133,"LiteratureReferences":135},{"effectName":134,"effectType":26},"Antiemetic","\u003Cp>\u003Ca href=\"http:\u002F\u002Fonlinelibrary.wiley.com\u002Fdoi\u002F10.1111\u002Fj.1476-5381.2011.01621.x\u002Ffull\">Cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT1A somatodendritic autoreceptors in the dorsal raphe nucleus\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs00213-010-2157-4\">Interaction between non-psychotropic cannabinoids in marihuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews\u003C\u002Fa>\u003Cbr>\u003Cbr>\u003C\u002Fp>",{"effectName":137,"LiteratureReferences":139},{"effectName":138,"effectType":26},"Anti-inflamation - Neuroinflammatory diseases","\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.degruyter.com\u002Fview\u002Fj\u002Fjbcpp.2016.27.issue-3\u002Fjbcpp-2015-0071\u002Fjbcpp-2015-0071.xml\">Anti-inflammatory effects of the cannabidiol derivative dimethylheptyl-cannabidiol – studies in BV-2 microglia and encephalitogenic T cells\u003C\u002Fa>\u003Cbr>\u003C\u002Fp>",{"effectName":141,"LiteratureReferences":143},{"effectName":142,"effectType":26},"Osteoporosis - Bone Stimulant","\u003Cp>\u003Ca href=\"http:\u002F\u002Fethos.bl.uk\u002FOrderDetails.do?uin=uk.bl.ethos.589495\">Regulation of bone by cannabinoid and cannabinoid-like receptors\u003C\u002Fa>\u003Cbr>\u003C\u002Fp>",{"effectName":145,"LiteratureReferences":147},{"effectName":146,"effectType":26},"Analgesic","\u003Cp>\u003Ca href=\"http:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F23141881\">An open-label extension study to investigate the long-term safety and tolerability of THC\u002FCBD oromucosal spray and oromucosal THC spray in patients with terminal cancer-related pain refractory to strong opioid analgesics\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"http:\u002F\u002Fonlinelibrary.wiley.com\u002Fdoi\u002F10.1111\u002Fj.1365-2044.2004.03674.x\u002Ffull\">Initial experiences with medicinal extracts of cannabis for chronic pain: results from 34 ‘N of 1’ studies\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"http:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F24420962\">A double-blind, randomized, placebo-controlled, parallel group study of THC\u002FCBD spray in peripheral neuropathic pain treatment\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"http:\u002F\u002Fwww.sciencedirect.com\u002Fscience\u002Farticle\u002Fpii\u002FS0885392409007878\">Multicenter, Double-Blind, Randomized, Placebo-Controlled, Parallel-Group Study of the Efficacy, Safety, and Tolerability of THC:CBD Extract and THC Extract in Patients With Intractable Cancer-Related Pain\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"http:\u002F\u002Fwww.sciencedirect.com\u002Fscience\u002Farticle\u002Fpii\u002FS0014299904012348\">(+)-Cannabidiol analogues which bind cannabinoid receptors but exert peripheral activity only\u003C\u002Fa>\u003Cbr>\u003Cbr>\u003Cbr>\u003Cbr>\u003Cbr>\u003C\u002Fp>",{"effectName":149,"LiteratureReferences":151},{"effectName":150,"effectType":26},"Parkinson’s Disease","\u003Cp>\u003Ca href=\"http:\u002F\u002Fwww.tandfonline.com\u002Fdoi\u002Fabs\u002F10.3109\u002F00207458608985678\">Open label evaluation of cannabidiol in dystonic movement disorders\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"http:\u002F\u002Fjournals.sagepub.com\u002Fdoi\u002Fabs\u002F10.1177\u002F0269881114550355\">Effects of cannabidiol in the treatment of patients with Parkinson’s disease: An exploratory double-blind trial\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003Cbr>    \u003Cbr>\u003C\u002Fp>",{"effectName":153,"LiteratureReferences":155},{"effectName":154,"effectType":26},"Antiinflammatory - Pathological memory T cells and in Autoimmune diseases","\u003Cp>Pathological memory T cells and in Autoimmune diseases\u003Cbr>\u003C\u002Fp>",{"effectName":157,"LiteratureReferences":159},{"effectName":158,"effectType":26},"Anxiolytic","\u003Cp>\u003Ca href=\"https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs00213-012-2955-y\">Cannabidiol enhances consolidation of explicit fear extinction in humans\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Ca href=\"http:\u002F\u002Fwww.sciencedirect.com\u002Fscience\u002Farticle\u002Fpii\u002FS0022395612002452\">Cannabidiol blocks long-lasting behavioral consequences of predator threat stress: Possible involvement of 5HT1A receptors\u003C\u002Fa>\u003Cbr>\u003Cbr>\u003C\u002Fp>",{"effectName":161,"LiteratureReferences":163},{"effectName":162,"effectType":26},"Antipsychotic","\u003Cp>\u003Ca href=\"http:\u002F\u002Fwww.sciencedirect.com\u002Fscience\u002Farticle\u002Fpii\u002FS0920996411002246\">Cannabis with high cannabidiol content is associated with fewer psychotic experiences\u003C\u002Fa>\u003Cbr>\u003C\u002Fp>",{"effectName":165,"LiteratureReferences":167},{"effectName":166,"effectType":26},"Antipsychotic - Schizophrenia","\u003Cp>\u003Ca href=\"http:\u002F\u002Fwww.nature.com\u002Ftp\u002Fjournal\u002Fv2\u002Fn3\u002Ffull\u002Ftp201215a.html\">Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia\u003C\u002Fa>\u003Cbr>\u003C\u002Fp>",{"effectName":169,"LiteratureReferences":171},{"effectName":170,"effectType":26},"Antiinflammatory - Sepsis","\u003Cp>\u003Ca href=\"http:\u002F\u002Fonlinelibrary.wiley.com\u002Fdoi\u002F10.1111\u002Fj.1365-2982.2008.01114.x\u002Ffull\">Effect of cannabidiol on sepsis-induced motility disturbances in mice: involvement of CB1 receptors and fatty acid amide hydrolase\u003C\u002Fa>\u003Cbr>\u003C\u002Fp>",{"effectName":173,"LiteratureReferences":175},{"effectName":174,"effectType":26},"Antispasticity","\u003Cp>\u003Ca href=\"http:\u002F\u002Fonlinelibrary.wiley.com\u002Fdoi\u002F10.1111\u002Fj.1468-1331.2006.01639.x\u002Ffull\">Randomized controlled trial of cannabis-based medicine in spasticity caused by multiple sclerosis\u003C\u002Fa>\u003Cbr>\u003C\u002Fp>",{"effectName":177,"LiteratureReferences":179},{"effectName":178,"effectType":26},"Neuroprotectant - Spinal injury","\u003Cp>\u003Ca href=\"https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs12640-011-9273-8\">Cannabidiol-treated Rats Exhibited Higher Motor Score After Cryogenic Spinal Cord Injury\u003C\u002Fa>\u003Cbr>\u003C\u002Fp>",{"effectName":181,"LiteratureReferences":183},{"effectName":182,"effectType":26},"Antiinflammatory  - Uveitis","\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpmc\u002Farticles\u002FPMC2592995\u002F\">Neuroprotective effects of cannabidiol in endotoxin-induced uveitis: critical role of p38 MAPK activation\u003C\u002Fa>\u003Cbr>\u003C\u002Fp>",1785925827479]